ASTRAZENECA PLC (AZN) Stock Analysis

Price updated 4 days ago · SEC data refreshed 3 months ago · Not investment advice

ASTRAZENECA PLC

AZN Healthcare Pharmaceuticals📄 SEC filings ↗ CUSIP 046353108
Valuation N/A
▾ What's in the 32/100 risk score? (higher = riskier)
Fundamental health (43%) 20/100 → +8.6
leverage 20/100
Smart money (short interest + insider buying) (31%) 45/100 → +14.1
Macro backdrop (VIX, curve, credit, fear/greed + week-over-week momentum) (26%) 35/100 → +9.0
early-warning: macro conditions deteriorating week-over-week
Total32/100

Contributions (weight × component score) sum to the total. This near-term score now includes fundamental health (leverage, FCF trend). See the Financial Health section for the full balance-sheet read.

💵 Price $160.17 · 4 days ago 📄 Financials SEC EDGAR · refreshed 3 months ago

How to read AZN

We are not publishing an intrinsic value for this one — the section below says exactly why. Everything on this page that comes straight from the filings and the tape is still here; treat the missing valuation as a known gap, not as a verdict on the business.

Where to start — the sections that matter most for this stock
  1. 1 Reported earnings & margins ↓
    What the company actually reported — unaffected by the valuation being held.
  2. 2 Balance sheet & book value ↓
    Assets, liabilities and equity as filed.
  3. 3 Who's selling & betting against it ↓
    Insider and short-interest behaviour needs no valuation model.
Or — what are you trying to decide?
A note on process: fear-driven decisions — including fear of missing out — tend to be the expensive ones. A stock up 10% a day for three days is excitement, not evidence. Whichever reader you are, the data below is there to be checked before anything is decided.
🚀
"It's surging — should I chase it?"
The momentum / FOMO trade. Before you chase, see whether the people who know it best are quietly selling into the rally.
🏷️
"Is it a cheap bargain?"
The deep-value trade. How far below assets and our value it trades — and whether it's cheap for a reason.
ⓘ A share-count quirk blocked the per-share math

The share count we read for AZN looks wrong — common for multi-class / founder-controlled filers that report shares per share-class. That makes per-share figures (including intrinsic value) misleading, so we suppressed them. The company's total financials below are sound.

What to use instead: Lean on the totals — revenue, net income, cash flow — and the balance sheet. Multi-class share counts are being corrected; once fixed, the per-share valuation returns automatically.

This note is only about the single DCF fair-value number — AZN's full financial statements, health scores, and written analysis are all below.

Loading insider & short-seller data…
Checking filings for failure warnings…

How to read a company this small

This is a clinical-stage biotech with little or no revenue. Standard DCF requires future cash flows to discount — there's nothing to discount yet. The value is entirely in the drug pipeline and the probability that it works.

✅ What actually drives value for this kind of company
  • Drug pipeline — phase of each candidate (Phase I → II → III → FDA approval); each phase has historical success probabilities
  • Total Addressable Market (TAM) of the lead indication — bigger market = bigger payoff if approved
  • Cash runway — months of cash left at current burn rate before they need to raise more (and dilute shareholders)
  • Strategic partnerships — Big Pharma collaborations validate the science and bring milestone payments
  • Patent / exclusivity timeline — how long until generics if approved
  • Insider holdings + management track record — biotech execs with prior wins are a real signal
❌ Metrics that DON'T apply (ignore these even if you see them below)

P/E, P/B, EV/Sales, ROE — meaningless when there's no revenue or earnings. DCF outputs are nonsense.

📚 Where to actually look

ClinicalTrials.gov for trial status. The 10-K's "Pipeline" section. Recent press releases on Phase II/III readouts. Conferences like JPM Healthcare or ASCO.

Classified as Clinical-Stage Biotech (confidence 85%). Disagree? An admin can override via the post edit screen.

Quality & solvency checks

Cheap stocks can be cheap for a reason. These screens warn when a low valuation comes paired with structural fragility.

Altman Z-Score?Altman Z-Score — A bankruptcy-risk score combining 5 financial ratios into one number. Predictive of bankruptcy within 2 years.
Why it matters: Cheap-looking stocks (low P/E or P/B) often have low Z-scores because the market knows the company is dying. Z-score warns you before you fall into a value trap.
Reference: > 3.0 = safe zone · 1.81–3.0 = grey zone · < 1.81 = distress zone
Full explanation →
Not available for this filer

The Z-score needs working capital, retained earnings, EBIT, sales and total assets from the latest balance sheet, and at least one of those isn't reported in machine-readable form here — common for foreign private issuers. We leave it blank rather than compute a distress verdict from an estimated input. It doesn't affect the reported figures in the financial tables below.

Piotroski F-Score?Piotroski F-Score — A 9-point quality checklist scoring profitability, leverage, and operating efficiency.
Why it matters: High score = fundamentals improving. Low score = deteriorating. Especially powerful for filtering cheap stocks: cheap + high F-score historically outperforms; cheap + low F-score is often a value trap.
Reference: 7–9 = strong · 4–6 = mediocre · 0–3 = weak
Full explanation →
Not available for this filer

The F-score compares two consecutive years of income, cash-flow and balance-sheet data. We have 5 years of income data for this filer, but no machine-readable cash-flow statement — so several of the nine checks have no input at all. We show nothing rather than score a partial year against itself. The reported figures in the financial tables below are unaffected.

Price$160.17
Model IVNot applicable — DCF couldn't price this stock. The other valuation lenses on this page (reverse-DCF, peers, sector lens — whichever apply to this filer) carry the read instead.

A standard discounted cash flow?DCF — Discounted Cash Flow — sums up all future cash a business will produce, adjusted for the fact that future dollars are worth less than dollars today.
Why it matters: It is the most fundamentally honest valuation method when applicable — but only works for companies with predictable, positive cash flow.
Reference: Best for: mature, profitable businesses. Fails for: pre-profit growth, banks, REITs.
Full explanation →
(DCF) valuation is not meaningful for AstraZeneca due to its negative free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
, as indicated by the 'FCF negative' flag. The model projects future cash flows from revenue trajectory, but currently implies no positive equity value, making valuation speculative. Investors are likely betting on the success of its drug pipeline and future revenue growth. The primary quantifiable risk is the continued negative free cash flow, which could necessitate further capital raises.

⚠️ FCF negative: revenue/margin growth model projects future cash flows from revenue trajectory.

As of 3 months ago

Anatomy of a share

What you're buying per share. Bars are at the same scale so you can see the relative size of revenue, costs, cash flow, and debt — not just read them in a table.

Per-share economics aren't reliable for this filer. Its income statement or share count isn't fully reported to SEC EDGAR (common for foreign private issuers and thinly-disclosed OTC names), so we don't break it down per share here — the figures would be misleading. See the financial tables below for what is reported.

What you actually need to decide

Every stock price is a disagreement. Here's the single thing that must go right for the bulls, the single thing that breaks the thesis, and the concrete signposts to watch so you can update your view as real results arrive.

🐂 The Bull Case
The most important thing that must go right for the stock is for its extensive drug pipeline to yield successful, high-revenue products, leading to sustained positive free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
and validating the revenue trajectory model.
🐻 The Bear Case
The biggest fundamental risk is the continued negative free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
, as indicated by the 'FCF negative' flag, which implies that the company is not generating sufficient cash from operations and may require further financing, potentially diluting shareholders.
📌 Signposts to watch — update your view as these print
  • Regulatory approvals for late-stage pipeline drugs
  • Launch success and sales growth of new products
  • Improvement in free cash flow generation

The trend, in plain numbers (FY2024 → FY2025, latest reported)

Straight from the financial statements — no model, no opinion. For a small or unprofitable company, the direction of these numbers usually tells you more than any single valuation.

✅ Improving
  • Net income grew +45% to $10.23B.

Nothing was clearly worsening year-over-year.

Management & Leadership

Pascal Soriot has served as the Chief Executive Officer of AstraZeneca since October 2012, overseeing the company's strategic direction and global operations. He has been instrumental in focusing the company on key therapeutic areas and driving R&D efforts. Leif Johansson is the current Chairman of the Board.

Pascal Soriot
Chief Executive Officer
Leif Johansson
Chairman of the Board

What They Make

AstraZeneca PLC is a global, science-led biopharmaceutical company focused on the discovery, development, manufacturing, and commercialization of prescription medicines. Its products treat diseases in therapeutic areas such as oncology, cardiovascular, renal & metabolism, and respiratory & immunology.

End Markets

OncologyCardiovascular, Renal & MetabolismRespiratory & Immunology

Revenue Drivers

Oncology drug sales
Cardiovascular drug sales
Respiratory drug sales
Beta: 0.55

Why Is It Priced Like This?

Why Customers Pay

Provides innovative medicines for life-threatening diseases
Offers treatments across multiple therapeutic areas
Engages in extensive research and development for new therapies
No discounted-cash-flow value for this filer No machine-readable cash-flow statement in this filer's EDGAR submissions — common for foreign private issuers (20-F/6-K). That makes a discounted-cash-flow valuation impossible: there is no free cash flow to discount. It does not affect the income-statement or balance-sheet figures below.

What we use instead: earnings (P/E, EV/EBIT), book value (P/B) — computed from the figures this company does report, shown in the sections below. Those numbers are unaffected by the missing cash-flow data.

The market is likely pricing AstraZeneca based on expectations for its future drug pipeline success and revenue growth, rather than current cash flow, as indicated by the 'FCF?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
negative' health signal. The market may be assigning value to the potential blockbuster drugs in its late-stage pipeline, which is not in the model, and the long-term growth prospects from its R&D investments, despite the current lack of positive equity value in the model.

Business Model & Valuation

How They Make Money

Sales of patented prescription drugs
Licensing agreements and collaborations
Development and commercialization of new therapies

AstraZeneca typically funds itself through a combination of operating cash flows, debt, and equity, with a focus on reinvesting in R&D. Dividend policy is not specified in the FLAGS.

Growth / Revenue DCF

No cash flow statement data available - using revenue/margin growth model as fallback.

Show advanced inputs
Revenue Growth15.0%

What this model does NOT do: this is a consolidated owner-earnings FCF model. Standalone segment assumptions: none. It does not project its revenue segments independently; their combined effect is embedded in the historical revenue and cash-flow trend the model extrapolates. The calculator above can only approximate a segment's impact through the single consolidated growth rate — it cannot model any one line separately. For a true segment-level view, build a separate model from the company's segment disclosures.

Maturity & Competitive Position

Growth-stage life sciences

Moat Signals

Extensive R&D pipeline
Patent protection on key drugs
Global distribution network

Net income has been positive for the latest period and 5 out of 5 years, indicating profitability despite negative FCF?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
.

Geography & Markets

AstraZeneca is a global biopharmaceutical company with significant operations and sales across North America, Europe, and emerging markets, though specific geographic revenue percentages are not available from current data sources.

Geographic Risks

Regulatory approval risks for new drugs
Patent expiration and generic competition

Market Signals

These are timing signals, not value signals — they describe the stock's recent price behavior, not what the business is worth. Use them for the "the thesis looks good, but is now the moment?" question. Each tile below explains what it's saying.

Model neutral, tape neutral - aligned.
RSI?RSI — Relative Strength Index — a 0-100 momentum gauge. Above 70 = overbought; below 30 = oversold.
Why it matters: Short-term contrarian indicator. Extreme readings often precede mean reversion, though not always.
Reference: 30–70 normal · >70 overbought · <30 oversold
Full explanation →
(14)
46.4NeutralMomentum is balanced — neither overbought nor oversold.
MACD?MACD — Moving Average Convergence Divergence — compares a fast and a slow price trend to gauge momentum direction.
Why it matters: When the fast line crosses above the slow line, short-term momentum is turning up; below, turning down. A timing cue, not a value signal.
Reference: Line above signal = bullish momentum · below = bearish
Full explanation →
BullishLine above signalThe fast trend is above the slow trend — short-term momentum is currently upward.
50-Day Average$190.88Price below (-16.1%)Price below its 50-day average = near-term downtrend.
200-Day Average$180.58Price belowThe 200-day line is the long-term trend divider — above it is generally considered a bull market for the stock.
50 vs 200 CrossGolden50-day above 200-dayA "golden cross" — the medium trend has overtaken the long trend (often read as bullish).

Technicals describe price, not the business. A great company can have a "bearish" tape (a buying chance) and a weak one a "bullish" tape (a trap). Pair these with the valuation and health sections above.

Data Quality & Risk Flags (8 notes — click to expand/collapse)

Guardrail Notes (8)
  • FCF negative: revenue/margin growth model projects future cash flows from revenue trajectory.
  • INVARIANT: weighted IV is non-positive. Model may not be appropriate.
  • Model implies no positive equity value under these assumptions. Valuation is speculative/low-confidence.
  • Shares from unknown — per-share values may be less accurate.
  • Illiquidity discount 25% applied (small/micro-cap — harder to exit, demand a margin).
  • Shares/market cap missing or defaulted; per-share valuation unreliable.
  • Shares defaulted to 1; IV is NOT meaningful — treat as data-unavailable.
  • DATA UNAVAILABLE: per-share values suppressed due to missing/unreliable shares data.

Financial Statements (5-year tables — click to expand)

From ASTRAZENECA PLC's SEC filings (EDGAR).

Income (5yr)

YearRevenueNet IncomeEPS
202510.2B
20247.0B
20236.0B
20223.3B
2021115.0M

Balance Sheet

Total Assets114.1B
Total Liabilities65.4B
Equity

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PG
Methodology by Pouyan Golshani, MD — founder of Gighz. Savng was built by a physician for busy professionals: every number on this page comes from SEC filings (EDGAR) and FINRA data through transparent, rules-based models — no analyst opinions, no hidden inputs. How we calculate every number →
⚠️ Not investment advice. Automated model outputs, last refreshed May 30, 2026 (the analysis-refresh date, not the latest filing period). All models have blind spots. Full disclaimer →
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