XORTX Therapeutics Inc. (XRTX) Stock Analysis

Price updated today · SEC data refreshed 11 days ago · Not investment advice

XORTX Therapeutics Inc.

XRTX Healthcare Pharmaceuticals📄 SEC filings ↗
Speculative
▾ What's in the 30/100 risk score? (higher = riskier)
Smart money (short interest + insider buying) (55%) 31/100 → +17.1
Macro backdrop (VIX, curve, credit, fear/greed + week-over-week momentum) (45%) 28/100 → +12.6
Total30/100

Contributions (weight × component score) sum to the total. This near-term score now includes fundamental health (leverage, FCF trend). See the Financial Health section for the full balance-sheet read.

💵 Price $2.16 · today 📄 Financials SEC EDGAR · refreshed 11 days ago

How to read XRTX (speculative micro-cap)

No model can pin a precise fair value on a company this small — but that does not mean there is nothing to learn. The useful questions are what the price is betting on, and whether the company can survive long enough to deliver it.

Where to start — the sections that matter most for this stock
  1. 1 Reverse-DCF — what growth the price assumes ↓
    The single most useful number here: it backs out the growth the market is paying for. If that figure is "historically unprecedented," the price is running on hype, not fundamentals.
  2. 2 Cash runway ↓
    A pre-profit micro-cap lives or dies on whether it can fund itself to profitability before running out of money and diluting you.
  3. 3 The raw financial statements + the 10-K ↓
    At this scale, the actual numbers, insider ownership, and share-count trend tell you more than any ratio.
Or — what are you trying to decide?
One rule first: never trade out of fear — and that includes the fear of missing out. A stock up 10% a day for three days is excitement, not data. If you can't point to the evidence behind a trade, you're more likely to lose. So whichever of these you are, check the data below before you act.
🚀
"It's surging — should I chase it?"
The momentum / FOMO trade. Before you chase, see whether the people who know it best are quietly selling into the rally.
🏷️
"Is it a cheap bargain?"
The deep-value trade. How far below assets and our value it trades — and whether it's cheap for a reason.
ⓘ XRTX is a thinly-disclosed company trading over-the-counter

It files little or nothing with the SEC — so our cash-flow models, financial statements, and U.S. insider data (Form 4) don't apply. What's still real: the live U.S. price and short positioning. Here's what we could pull from other sources:

XORTX Therapeutics Inc. is a pharmaceutical company with two clinically advanced products in development – XRx-008 for Autosomal Dominant Polycystic Kidney Disease (ADPKD), XRx-101 for Coronavirus / COVID-19 infection and XRx-225 is a pre-clinical stage program for Type 2 Diabetic Nephropathy (T2DN). XORTX is working to advance its clinic…

📑 Read the real filings: latest SEC 6-K ↗

Identity, share count and tier from FINRA + OTC Markets; not a substitute for the home-market financial statements. Thin U.S. disclosure + OTC trading is itself a risk factor.

ⓘ Why does XRTX trade at $2.16?

XORTX Therapeutics Inc. has 13.0 million shares outstanding. At $2.16 per share, the market values all outstanding XRTX equity at $28 million. That's market capitalization, not enterprise value — enterprise value also accounts for debt and cash (XRTX carries little or no debt, so the two are close here). The share price by itself tells you almost nothing — a company can pick any share price by splitting or issuing more shares. What matters is the total value (Market Cap?Market Cap — The total dollar value the market is assigning to the entire company.
Why it matters: This is the number that actually matters when comparing companies. Two companies with the same business but different share counts have the same market cap.
Reference: Mega cap >$200B · Large $10–200B · Mid $2–10B · Small $300M–2B · Micro <$300M
Full explanation →
) compared to what the business actually produces. This page values XRTX in Per Share?Per Share — A company-level figure divided by total shares — what one share represents.
Why it matters: Per-share metrics are the only way to fairly compare two companies with different share counts.
Full explanation →
economics — what each share represents of the underlying business. Play with the share-price calculator on the homepage →

Loading insider & short-seller data…

How to read a company this small

This is a clinical-stage biotech with little or no revenue. Standard DCF requires future cash flows to discount — there's nothing to discount yet. The value is entirely in the drug pipeline and the probability that it works.

✅ What actually drives value for this kind of company
  • Drug pipeline — phase of each candidate (Phase I → II → III → FDA approval); each phase has historical success probabilities
  • Total Addressable Market (TAM) of the lead indication — bigger market = bigger payoff if approved
  • Cash runway — months of cash left at current burn rate before they need to raise more (and dilute shareholders)
  • Strategic partnerships — Big Pharma collaborations validate the science and bring milestone payments
  • Patent / exclusivity timeline — how long until generics if approved
  • Insider holdings + management track record — biotech execs with prior wins are a real signal
❌ Metrics that DON'T apply (ignore these even if you see them below)

P/E, P/B, EV/Sales, ROE — meaningless when there's no revenue or earnings. DCF outputs are nonsense.

📚 Where to actually look

ClinicalTrials.gov for trial status. The 10-K's "Pipeline" section. Recent press releases on Phase II/III readouts. Conferences like JPM Healthcare or ASCO.

Classified as Clinical-Stage Biotech (confidence 85%). Disagree? An admin can override via the post edit screen.

⚠ Genuine comparables are scarce at this size, so peer multiples are unreliable here. Treat as rough context only — see 📍 What to focus on above.

How does XRTX stack up against its closest peers?

We take the 8 same-industry companies most similar to XRTX (similar size) and check what investors are paying for each dollar of their revenue (or profits). If XRTX is much more expensive on the same yardstick, that's a red flag — unless you have a specific reason it deserves a premium. For a leveraged business, FCF yield (in the table) is usually more reliable than EV/Sales, because revenue multiples ignore differences in margins and debt.

▾ What's "EV / Sales" in plain English?

EV (Enterprise Value) = market cap + total debt − cash. It's "what you'd pay to buy the entire company outright" — you pay the market cap to shareholders and take over their debt, but you keep their cash. EV is fairer than market cap alone because it includes the debt the new owner inherits.

EV / Sales = EV ÷ annual revenue. So "2.5×" means investors pay $2.50 of enterprise value per $1 of yearly sales. Higher = market is paying more per dollar of sales (usually because they expect future growth or fat margins).

p25 / median / p75 are the 25th, 50th (middle), and 75th percentile of the peers' multiples. Half the peers fall between p25 and p75. The median (p50) is the typical peer — that's the benchmark we compare to.

What peers trade at (p25 / median / p75)
EV / Sales?EV / Sales — For every $1 of yearly revenue, this is how many dollars investors pay to own the whole business (including debt).
Why it matters: Works for pre-profit growth companies where P/E and FCF don't apply. The most apples-to-apples cross-company multiple because it ignores accounting choices.
Reference: 1–3x for mature companies · 4–10x for software/SaaS · 10–20x for hypergrowth · >20x is rare and demanding
Full explanation →
7.9x / 8.2x / 16.8x

Bold middle number = median peer. Half the peers trade above it, half below. Computed over 8 same-industry peers; implausible multiples excluded.

What XRTX would be worth at the median peer's multiple
Peer-implied price isn't available for XRTX right now. The multiples table above still works as context.

⚠️ Important caveat: peer multiples only work if the peers are genuinely comparable. Always check the peer list below — if the auto-picker grabbed micro-caps or unrelated businesses, the comparison is noise. A medical-device giant priced against tiny biotech startups won't produce a useful signal.

▾ View peer list (8)
Ticker Company Industry Mcap EV/Sales EV/GP EV/EBIT FCF Yield
VTGN Vistagen Therapeutics, Inc. Pharmaceuticals $25M 51.4x
TXMD TherapeuticsMD, Inc. Pharmaceuticals $25M 8.2x 9.6%
TVRD Tvardi Therapeutics, Inc. Pharmaceuticals $32M
VYNE VYNE Therapeutics Inc. Pharmaceuticals $23M 39.9x
TPST Tempest Therapeutics, Inc. Pharmaceuticals $23M
VNRX VOLITIONRX LTD Pharmaceuticals $22M 16.8x 0.7%
TRAW Traws Pharma, Inc. Pharmaceuticals $22M 7.9x 9.8%
VERU VERU INC. Pharmaceuticals $38M

Quality & solvency checks

Cheap stocks can be cheap for a reason. These screens warn when a low valuation comes paired with structural fragility.

Altman Z-Score?Altman Z-Score — A bankruptcy-risk score combining 5 financial ratios into one number. Predictive of bankruptcy within 2 years.
Why it matters: Cheap-looking stocks (low P/E or P/B) often have low Z-scores because the market knows the company is dying. Z-score warns you before you fall into a value trap.
Reference: > 3.0 = safe zone · 1.81–3.0 = grey zone · < 1.81 = distress zone
Full explanation →
Not available for this filer

The Z-score needs working capital, retained earnings, EBIT, sales and total assets from the latest balance sheet, and at least one of those isn't reported in machine-readable form here — common for foreign private issuers. We leave it blank rather than compute a distress verdict from an estimated input. It doesn't affect the reported figures in the financial tables below.

Piotroski F-Score?Piotroski F-Score — A 9-point quality checklist scoring profitability, leverage, and operating efficiency.
Why it matters: High score = fundamentals improving. Low score = deteriorating. Especially powerful for filtering cheap stocks: cheap + high F-score historically outperforms; cheap + low F-score is often a value trap.
Reference: 7–9 = strong · 4–6 = mediocre · 0–3 = weak
Full explanation →
Not available for this filer

The F-score compares two consecutive years of income, cash-flow and balance-sheet data. We have 0 years of income data for this filer, but no machine-readable cash-flow statement or balance sheet — so several of the nine checks have no input at all. We show nothing rather than score a partial year against itself. The reported figures in the financial tables below are unaffected.

Price$2.16
Model IVNot applicable — DCF couldn't price this stock. See Reverse DCF and Football Field below.

A standard discounted cash flow?DCF — Discounted Cash Flow — sums up all future cash a business will produce, adjusted for the fact that future dollars are worth less than dollars today.
Why it matters: It is the most fundamentally honest valuation method when applicable — but only works for companies with predictable, positive cash flow.
Reference: Best for: mature, profitable businesses. Fails for: pre-profit growth, banks, REITs.
Full explanation →
(DCF) valuation is not meaningful for XORTX Therapeutics Inc. because the company exhibits negative free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
, indicating it is in a cash-burning growth stage. Valuing XRTX would require projecting future revenue growth and eventual profitability based on its drug pipeline. Investors are likely betting on successful clinical trial outcomes and regulatory approvals for its drug candidates. The biggest risk to our assumptions is that the model implies no positive equity value under current assumptions, suggesting high speculation.

⚠️ FCF negative: revenue/margin growth model projects future cash flows from revenue trajectory.

As of 11 days ago

Anatomy of a share

What you're buying per share. Bars are at the same scale so you can see the relative size of revenue, costs, cash flow, and debt — not just read them in a table.

Per-share economics aren't reliable for this filer. Its income statement or share count isn't fully reported to SEC EDGAR (common for foreign private issuers and thinly-disclosed OTC names), so we don't break it down per share here — the figures would be misleading. See the financial tables below for what is reported.

What you actually need to decide

Every stock price is a disagreement. Here's the single thing that must go right for the bulls, the single thing that breaks the thesis, and the concrete signposts to watch so you can update your view as real results arrive.

🐂 The Bull Case
The most important operating factor for XORTX is the successful progression of its lead drug candidates through clinical trials and subsequent regulatory approval, leading to future revenue generation.
🐻 The Bear Case
The biggest operating risk is the failure of drug candidates in clinical trials or an inability to secure regulatory approvals, which would lead to continued cash burn and no path to profitability.
📌 Signposts to watch — update your view as these print
  • Phase 2/3 clinical trial results for lead candidates
  • Regulatory submission and approval timelines
  • New partnership or licensing agreements

Management & Leadership

Dr. Allen E. Moore serves as the President and CEO of XORTX Therapeutics Inc. He is also the founder and Chairman of the Board. The company focuses on developing therapies for kidney disease.

Dr. Allen E. Moore
President and Chief Executive Officer

What They Make

XORTX Therapeutics Inc. develops novel therapies for progressive kidney disease and related conditions. The company aims to commercialize drug candidates for rare diseases, with pharmaceutical companies and healthcare systems being the ultimate payers.

End Markets

Kidney Disease TreatmentRare Disease TherapeuticsPharmaceutical Development

Revenue Drivers

Drug candidate development
Clinical trial success
Regulatory approvals
Market Cap: 28.0MBeta: 0.68

Why Is It Priced Like This?

Why Customers Pay

Addresses unmet medical needs in kidney disease
Potential for improved patient outcomes
Novel therapeutic approaches
No discounted-cash-flow value for this filer No machine-readable cash-flow statement in this filer's EDGAR submissions — common for foreign private issuers (20-F/6-K). That makes a discounted-cash-flow valuation impossible: there is no free cash flow to discount. It does not affect the income-statement or balance-sheet figures below.

The income statement and balance sheet are also too incomplete here to substitute another lens honestly, so this page carries price, momentum and disclosure facts only.

The market is pricing XORTX based on expectations for its drug pipeline and future commercialization success, rather than current cash flow, as indicated by its negative free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
. The market may be assigning value to potential drug pipeline catalysts, which is not in the model, anticipating future revenue streams from successful drug development and regulatory approvals.

Business Model & Valuation

How They Make Money

Drug candidate research and development
Licensing agreements for drug candidates
Potential future drug sales

The company primarily funds itself through equity raises, as it is in a cash-burning growth stage with negative free cash flow?Free Cash Flow (FCF) — Operating cash flow minus capital spending: cash left after a company covers operating costs, taxes and interest and reinvests in the business — but BEFORE repaying debt principal or paying dividends. The cash actually available to investors.
Why it matters: A company can show big profits on paper while burning through cash. FCF is what actually fills the bank account.
Reference: Healthy mature businesses convert 8–15% of revenue into FCF · Growth companies often negative
Full explanation →
and no dividends or buybacks.

Growth / Revenue DCF

No cash flow statement data available - using revenue/margin growth model as fallback.

Show advanced inputs
RevenueGrowth15.0%

What this model does NOT do: this is a consolidated owner-earnings FCF model. Standalone segment assumptions: none. It does not project its revenue segments independently; their combined effect is embedded in the historical revenue and cash-flow trend the model extrapolates. The calculator above can only approximate a segment's impact through the single consolidated growth rate — it cannot model any one line separately. For a true segment-level view, build a separate model from the company's segment disclosures.

Maturity & Competitive Position

Growth-stage life sciences

Moat Signals

Proprietary drug candidates
Specialized therapeutic focus
Regulatory exclusivity potential

Geography & Markets

XORTX Therapeutics Inc. is headquartered in Canada, with its research and development activities focused on global markets for its drug candidates. Exact geographic revenue mix is not available from current data sources.

Geographic Risks

Concentration risk on specific drug candidates
Regulatory approval risk across different jurisdictions

Market Signals

These are timing signals, not value signals — they describe the stock's recent price behavior, not what the business is worth. Use them for the "the thesis looks good, but is now the moment?" question. Each tile below explains what it's saying.

Model neutral, tape neutral - aligned.
RSI?RSI — Relative Strength Index — a 0-100 momentum gauge. Above 70 = overbought; below 30 = oversold.
Why it matters: Short-term contrarian indicator. Extreme readings often precede mean reversion, though not always.
Reference: 30–70 normal · >70 overbought · <30 oversold
Full explanation →
(14)
55.5NeutralMomentum is balanced — neither overbought nor oversold.
MACD?MACD — Moving Average Convergence Divergence — compares a fast and a slow price trend to gauge momentum direction.
Why it matters: When the fast line crosses above the slow line, short-term momentum is turning up; below, turning down. A timing cue, not a value signal.
Reference: Line above signal = bullish momentum · below = bearish
Full explanation →
BullishLine above signalThe fast trend is above the slow trend — short-term momentum is currently upward.
50-Day Average$2.14Price above (+0.7%)Price above its 50-day average = near-term uptrend.
200-Day Average$2.52Price belowThe 200-day line is the long-term trend divider — above it is generally considered a bull market for the stock.
50 vs 200 CrossDeath50-day below 200-dayA "death cross" — the medium trend is below the long trend (often read as bearish).

Technicals describe price, not the business. A great company can have a "bearish" tape (a buying chance) and a weak one a "bullish" tape (a trap). Pair these with the valuation and health sections above.

Data Quality & Risk Flags (5 notes — click to expand/collapse)

Guardrail Notes (5)
  • FCF negative: revenue/margin growth model projects future cash flows from revenue trajectory.
  • INVARIANT: weighted IV is non-positive. Model may not be appropriate.
  • Model implies no positive equity value under these assumptions. Valuation is speculative/low-confidence.
  • Illiquidity discount 25% applied (small/micro-cap — harder to exit, demand a margin).
  • Extreme valuation gap (P/IV null): result may be dominated by model assumptions, share count issues, or sector-specific dynamics. Treat as low confidence.

Financial Statements (5-year tables — click to expand)

From XORTX Therapeutics Inc.'s SEC filings (EDGAR).

Similar companies worth a look

Same sector and industry, similar fundamentals shape. Verify everything yourself — this list is computed mechanically and does not reflect our judgment about whether any of these are a good investment.

PG
Methodology by Pouyan Golshani, MD — founder of Gighz. Savng was built by a physician for busy professionals: every number on this page comes from SEC filings (EDGAR) and FINRA data through transparent, rules-based models — no analyst opinions, no hidden inputs. How we calculate every number →
⚠️ Not investment advice. Automated model outputs, last refreshed 11 days ago (the analysis-refresh date, not the latest filing period). All models have blind spots. Full disclaimer →
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