Surrozen, Inc./DE (SRZN) Stock Analysis

Price updated 5 days ago · SEC data refreshed 3 months ago · Not investment advice

Surrozen, Inc./DE

SRZN Healthcare Biotechnology📄 SEC filings ↗
Speculative
▾ What's in the 37/100 risk score? (higher = riskier)
Fundamental health (43%) 20/100 → +8.6
leverage 20/100
Smart money (short interest + insider buying) (31%) 65/100 → +20.4
Macro backdrop (VIX, curve, credit, fear/greed + week-over-week momentum) (26%) 33/100 → +8.5
Total37/100

Contributions (weight × component score) sum to the total. This near-term score now includes fundamental health (leverage, FCF trend). See the Financial Health section for the full balance-sheet read.

💵 Price $19.00 · 5 days ago 📄 Financials SEC EDGAR · refreshed 3 months ago

How to read SRZN (speculative micro-cap)

No model can pin a precise fair value on a company this small — but that does not mean there is nothing to learn. The useful questions are what the price is betting on, and whether the company can survive long enough to deliver it.

Where to start — the sections that matter most for this stock
  1. 1 Reverse-DCF — what growth the price assumes ↓
    The single most useful number here: it backs out the growth the market is paying for. If that figure is "historically unprecedented," the price is running on hype, not fundamentals.
  2. 2 Cash runway ↓
    A pre-profit micro-cap lives or dies on whether it can fund itself to profitability before running out of money and diluting you.
  3. 3 The raw financial statements + the 10-K ↓
    At this scale, the actual numbers, insider ownership, and share-count trend tell you more than any ratio.
Or — what are you trying to decide?
A note on process: fear-driven decisions — including fear of missing out — tend to be the expensive ones. A stock up 10% a day for three days is excitement, not evidence. Whichever reader you are, the data below is there to be checked before anything is decided.
🚀
"It's surging — should I chase it?"
The momentum / FOMO trade. Before you chase, see whether the people who know it best are quietly selling into the rally.
🏷️
"Is it a cheap bargain?"
The deep-value trade. How far below assets and our value it trades — and whether it's cheap for a reason.
ⓘ Using the right valuation lens for this business type

Standard DCF doesn't fit SRZN well — but that's expected for this kind of business. The Rule of 40 (Pre-Profit Growth) Lens below uses the metrics actually used by analysts who value biotechnology. Reverse DCF + Football Field also work as cross-checks.

Loading insider & short-seller data…
Checking filings for failure warnings…

How to read a company this small

This is a clinical-stage biotech with little or no revenue. Standard DCF requires future cash flows to discount — there's nothing to discount yet. The value is entirely in the drug pipeline and the probability that it works.

✅ What actually drives value for this kind of company
  • Drug pipeline — phase of each candidate (Phase I → II → III → FDA approval); each phase has historical success probabilities
  • Total Addressable Market (TAM) of the lead indication — bigger market = bigger payoff if approved
  • Cash runway — months of cash left at current burn rate before they need to raise more (and dilute shareholders)
  • Strategic partnerships — Big Pharma collaborations validate the science and bring milestone payments
  • Patent / exclusivity timeline — how long until generics if approved
  • Insider holdings + management track record — biotech execs with prior wins are a real signal
❌ Metrics that DON'T apply (ignore these even if you see them below)

P/E, P/B, EV/Sales, ROE — meaningless when there's no revenue or earnings. DCF outputs are nonsense.

📚 Where to actually look

ClinicalTrials.gov for trial status. The 10-K's "Pipeline" section. Recent press releases on Phase II/III readouts. Conferences like JPM Healthcare or ASCO.

Classified as Clinical-Stage Biotech (confidence 85%). Disagree? An admin can override via the post edit screen.

Quality & solvency checks

Cheap stocks can be cheap for a reason. These screens warn when a low valuation comes paired with structural fragility.

Altman Z-Score?Altman Z-Score — A bankruptcy-risk score combining 5 financial ratios into one number. Predictive of bankruptcy within 2 years.
Why it matters: Cheap-looking stocks (low P/E or P/B) often have low Z-scores because the market knows the company is dying. Z-score warns you before you fall into a value trap.
Reference: > 3.0 = safe zone · 1.81–3.0 = grey zone · < 1.81 = distress zone
Full explanation →
Not available for this filer

The Z-score needs working capital, retained earnings, EBIT, sales and total assets from the latest balance sheet, and at least one of those isn't reported in machine-readable form here — common for foreign private issuers. We leave it blank rather than compute a distress verdict from an estimated input. It doesn't affect the reported figures in the financial tables below.

Piotroski-style checks (partial — not a standard F-score)
3 passed · 5 failed · 1 n/a
Partial result, not a standard F-score: 3 of 8 measurable checks passed. 1 of the 9 standard checks couldn't be measured, so this is scored out of 8, not 9 — it isn't comparable to a published F-score.
▾ The checks — what passed, what didn't (and what we couldn't measure)
  • Positive net income
    Net income -$242.0M in FY2025.
    Why this matters: Does the company actually earn a profit? Sustained losses eventually force it to raise money — diluting you — or take on debt.
  • Positive operating cash flow
    Operating cash flow -$30.2M (was -$17.6M the prior year).
    Why this matters: Profit can be an accounting figure; cash from running the business is harder to fake. Negative operating cash flow means the core business consumes cash and must be funded externally.
  • Cash flow backs up reported profit
    Operating cash flow -$30.2M vs net income -$242.0M.
  • Return on assets improving
    Return on assets -245.1% vs -131.1% a year ago.
    Why this matters: Is the company squeezing more profit out of each dollar of assets than last year? Rising = getting more efficient; falling = the opposite.
  • Debt load (vs assets)
    The filing reports no interest-bearing debt in either year (total assets $98.7M).
  • Short-term liquidity (current ratio)
    Current ratio 9.22x vs 5.32x a year ago.
  • Share count (dilution)
    Share count rose 155.0% (0.0M → 0.0M year-over-year).
    Why this matters: Issuing lots of new shares splits the pie into more pieces, shrinking your slice. Stable or falling share count protects existing owners.
  • · Pricing power (gross margin) (n/a — data not reported; not scored)
  • Sales per asset (asset turnover)
    Asset turnover 0.04x vs 0.22x a year ago.
    Why this matters: Asset turnover measures how much revenue each dollar of assets generates. Rising = more productive use of the asset base.

Missing data is never counted as a pass or a fail — it's shown as n/a and excluded from the denominator. Each check compares the company against its own prior year.

Cash Runway
3.0 yrs
COMFORTABLE — 2+ years at the current burn

Plain English: the company holds about $89M in cash and is burning roughly $30M/year in operations. At that pace, the cash lasts 3.0 yrs before it must raise capital (diluting shareholders), take on debt, or cut spending.

Assumes constant burn and ignores financing/asset sales. For pre-profit biotech and growth companies, this matters more than a DCF — a great drug pipeline is worthless if they run out of money before approval.

Price$19.00
Model IVNot applicable — DCF couldn't price this stock. The other valuation lenses on this page (reverse-DCF, peers, sector lens — whichever apply to this filer) carry the read instead.

A standard discounted cash flow?DCF — Discounted Cash Flow — sums up all future cash a business will produce, adjusted for the fact that future dollars are worth less than dollars today.
Why it matters: It is the most fundamentally honest valuation method when applicable — but only works for companies with predictable, positive cash flow.
Reference: Best for: mature, profitable businesses. Fails for: pre-profit growth, banks, REITs.
Full explanation →
(DCF) valuation is not meaningful for Surrozen, Inc. because the company exhibits negative net income and operating cash flow, indicating it is not yet profitable and is burning cash. Valuing SRZN would require projecting the success and commercialization timeline of its drug pipeline, which is highly speculative. Investors are likely betting on the potential of its Wnt pathway modulation technology. The #1 quantifiable risk is the continued negative operating cash flow, which could deplete its cash runway if not offset by successful pipeline development or further financing.

⚠️ Revenue declining

As of 3 months ago

Anatomy of a share

What you're buying per share. Bars are at the same scale so you can see the relative size of revenue, costs, cash flow, and debt — not just read them in a table.

Per-share economics aren't reliable for this filer. Its income statement or share count isn't fully reported to SEC EDGAR (common for foreign private issuers and thinly-disclosed OTC names), so we don't break it down per share here — the figures would be misleading. See the financial tables below for what is reported.

What you actually need to decide

Every stock price is a disagreement. Here's the single thing that must go right for the bulls, the single thing that breaks the thesis, and the concrete signposts to watch so you can update your view as real results arrive.

🐂 The Bull Case
The company must achieve positive clinical trial results for its lead drug candidates, demonstrating efficacy and safety, to validate its technology and attract further investment or partnership opportunities.
🐻 The Bear Case
Continued negative operating cash flow without significant pipeline progress or new funding sources will deplete its cash reserves, posing a going concern risk.
📌 Signposts to watch — update your view as these print
  • Announcement of positive Phase 1/2 clinical trial data
  • Formation of new strategic development partnerships
  • Successful equity financing rounds to extend cash runway

The trend, in plain numbers (FY2024 → FY2025, latest reported)

Straight from the financial statements — no model, no opinion. For a small or unprofitable company, the direction of these numbers usually tells you more than any single valuation.

⚠ Worsening
  • Revenue fell -67% to $3.5M.
  • Free cash flow is negative at -$34.2M — the cash burn widened vs last year.
  • Still unprofitable at -$242.0M — loss widening.

Nothing was clearly improving year-over-year.

Management & Leadership

Surrozen, Inc. is led by Craig Parker, who serves as its President and Chief Executive Officer. He has been instrumental in guiding the company's strategic direction in developing novel regenerative medicines. The company focuses on Wnt pathway modulation.

Craig Parker
President and Chief Executive Officer
Wen-Chen Yean
Chief Scientific Officer

What They Make

Surrozen, Inc. is a biotechnology company developing novel regenerative medicines that modulate the Wnt pathway to repair tissues and organs. Its products are aimed at treating diseases with unmet medical needs.

End Markets

Regenerative MedicineBiopharmaceutical DevelopmentTherapeutic Drug Discovery

Revenue Drivers

Drug candidate milestones
Licensing agreements
Future product sales
Beta: 1.00

Why Is It Priced Like This?

Why Customers Pay

Addresses unmet medical needs for tissue repair
Offers potential for disease modification, not just symptom management
Leverages a fundamental biological pathway for broad applicability
No discounted-cash-flow value for this filer This company's reported free cash flow is negative, so a discounted-cash-flow valuation has no positive cash stream to discount. That is a fact about the business, not missing data — the reported figures below are complete.

What we use instead: earnings (P/E, EV/EBIT), book value (P/B) — computed from the figures this company does report, shown in the sections below. Those numbers are unaffected by the missing cash-flow data.

The market is pricing SRZN based on the future potential of its drug pipeline rather than current financial performance, as evidenced by its negative net income and operating cash flow. The market may be assigning value to the potential for successful clinical trial outcomes and eventual commercialization of its Wnt pathway modulators, which is not in the model. Expectations for future revenue growth from successful drug development are likely driving investor interest, despite the company's current cash burn.

Business Model & Valuation

How They Make Money

Advancing proprietary drug candidates through clinical trials
Forming strategic partnerships for co-development or licensing
Potential future sales of approved therapeutic products

The company funds itself primarily through equity raises and strategic partnerships, given its current negative operating cash flow and lack of dividends or buybacks.

Growth / Revenue DCF

Negative free cash flow: revenue/margin growth model used - standard FCF DCF is unreliable for companies still scaling.

Show advanced inputs
Revenue Growth15.0%

What this model does NOT do: this is a consolidated owner-earnings FCF model. Standalone segment assumptions: none. It does not project product, services and recurring/cloud lines independently; their combined effect is embedded in the historical revenue and cash-flow trend the model extrapolates. The calculator above can only approximate a segment's impact through the single consolidated growth rate — it cannot model any one line separately. For a true segment-level view, build a separate model from the company's segment disclosures.

Maturity & Competitive Position

Growth-stage life sciences

Moat Signals

Proprietary Wnt pathway modulation technology
Pipeline of novel drug candidates
Intellectual property around specific therapeutic targets

Net income and operating cash flow have been negative in the latest period and for 0/5 years, indicating a pre-profitability stage.

Geography & Markets

Surrozen, Inc. is headquartered in the United States, with its research and development activities primarily based there. Specific geographic revenue mix is not available from current data sources, but its focus is on global therapeutic markets.

Geographic Risks

Concentration risk in a single therapeutic pathway (Wnt)
Regulatory approval risk for novel drug candidates

Market Signals

These are timing signals, not value signals — they describe the stock's recent price behavior, not what the business is worth. Use them for the "the thesis looks good, but is now the moment?" question. Each tile below explains what it's saying.

Model neutral, tape neutral - aligned.
RSI?RSI — Relative Strength Index — a 0-100 momentum gauge. Above 70 = overbought; below 30 = oversold.
Why it matters: Short-term contrarian indicator. Extreme readings often precede mean reversion, though not always.
Reference: 30–70 normal · >70 overbought · <30 oversold
Full explanation →
(14)
40.8NeutralMomentum is balanced — neither overbought nor oversold.
MACD?MACD — Moving Average Convergence Divergence — compares a fast and a slow price trend to gauge momentum direction.
Why it matters: When the fast line crosses above the slow line, short-term momentum is turning up; below, turning down. A timing cue, not a value signal.
Reference: Line above signal = bullish momentum · below = bearish
Full explanation →
BearishLine below signalThe fast trend is below the slow trend — short-term momentum is currently downward.
50-Day Average$28.96Price below (-34.4%)Price below its 50-day average = near-term downtrend.
200-Day Average$20.51Price belowThe 200-day line is the long-term trend divider — above it is generally considered a bull market for the stock.
50 vs 200 CrossGolden50-day above 200-dayA "golden cross" — the medium trend has overtaken the long trend (often read as bullish).

Technicals describe price, not the business. A great company can have a "bearish" tape (a buying chance) and a weak one a "bullish" tape (a trap). Pair these with the valuation and health sections above.

Data Quality & Risk Flags (5 notes — click to expand/collapse)

HIGH Revenue declining
Guardrail Notes (4)
  • FCF negative: revenue/margin growth model projects future cash flows from revenue trajectory.
  • Illiquidity discount 7% applied (small/micro-cap — harder to exit, demand a margin).
  • Extreme valuation (P/IV withheld — see the note above); output dominated by data/units issue (often a multi-class share-count mismatch). Suppressed.
  • DATA UNAVAILABLE: per-share values suppressed due to missing/unreliable shares data.

Financial Statements (5-year tables — click to expand)

From Surrozen, Inc./DE's SEC filings (EDGAR).

Income (5yr)

YearRevenueNet IncomeEPS
20253.5M-242.0M$-32.37
202410.7M-63.6M$-21.67
2023-43.0M$-21.33
202212.5M-36.0M$-15.56
2021-54.6M$-2.21

Cash Flow (5yr)

YearOperating CFCapEx− SBC & adj.Free Cash Flow
2025 -30.2M 128,000 3.8M -34.2M
2024 -17.6M 26,000 4.1M -21.8M
2023 -40.4M 398,000 4.4M -45.1M
2022 -44.1M 728,000 4.5M -49.4M
2021 -48.8M 1.3M 2.3M -52.4M

How we define FCF: operating cash flow − capital expenditure − stock-based compensation (owner-earnings basis — SBC is a real cost to shareholders even though it's non-cash). Latest year: -30.2M − 128,000 − 3.8M (SBC & adj.) = -34.2M. This is the same owner-earnings FCF definition the valuation model uses, though the DCF's starting value is a projected from revenue × terminal margin, not this single year.

Balance Sheet

Total Assets98.7M
Total Liabilities286.5M
Equity-187.8M

Similar companies worth a look

Same sector and industry, similar fundamentals shape. Verify everything yourself — this list is computed mechanically and does not reflect our judgment about whether any of these are a good investment.

PG
Methodology by Pouyan Golshani, MD — founder of Gighz. Savng was built by a physician for busy professionals: every number on this page comes from SEC filings (EDGAR) and FINRA data through transparent, rules-based models — no analyst opinions, no hidden inputs. How we calculate every number →
⚠️ Not investment advice. Automated model outputs, last refreshed May 30, 2026 (the analysis-refresh date, not the latest filing period). All models have blind spots. Full disclaimer →
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